How https://www.ceesdekker.net can Save You Time, Stress, and Money.
How https://www.ceesdekker.net can Save You Time, Stress, and Money.
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‘Sure, which is about ideal. I seek for a Actual physical knowledge of biological methods within a base-up way. I do think you could potentially distinguish a few traces of study in my group at the moment. The first problems chromosome composition: How would you get a metre-extended DNA polymer folded and organised in such a microscopic mobile? Now we have made visualisation techniques that allow us to review how, by way of example, SMC proteins loop DNA (video clip on Youtube) so that you can Establish up chromosomes.
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To be a human being, I hold the biblical assignment to examine and use all the things in creation for the advantage of my neighbour. I don't working experience any conflict in between faith and science. On the contrary, my faith stimulates me to complete science, to get open up-minded in the world.’
Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metallic clusters
2015, discovery that condensin can be a very flexible protein framework; and 1st detection of DNA knots using nanopores
The coiled-coil from the human Rad50 DNA maintenance protein is made up of particular segments of amplified versatility
MATLAB codes for details processing can be obtained at . Julia codes utilized for numerical simulation are available at .
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2003, shown the 1st biosensors designed away from a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new procedure for fabricating reliable-condition nanopores for DNA translocation
Dekker started his investigate on solitary carbon nanotubes in 1993 when he setup a completely new line of investigate to review electrical transport by solitary organic cees dekker molecules involving nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was obtained in the collaboration With all the team of Nobel laureate Richard Smalley. STM and nanolithography tactics were utilized to show that these nanotubes are quantum wires at The one-molecule level, with superb physical Attributes.
Given that 2000 he moved to one-molecule biophysics and nanobiology, with exploration from scientific studies of DNA loop extrusion and supercoiling to DNA translocation through nanopores. Additional not too long ago his research has centered on learning chromatin composition and cell division with microbes on chip, although he is also aiming to ultimately Create synthetic cells from the bottom up.
Nanoscientist Cees Dekker is surely an amiable and flamboyant gentleman who appears much younger compared to the 62 decades he actually is – stylish Eyeglasses, psychedelic shirt, partaking smile – although not a single to squander time. He normally takes his time, but no more than needed.
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Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim in the pore is highlighted in pink, as well as a 3D rendering of the movement of the DNA rod is shown.